When it comes to the safety of hyaluronic acid injection, it is necessary for my friends to understand the past and present of hyaluronic acid.
Hyaluronic acid, also known as hyaluronic acid and hyaluronic acid, is a glycosaminoglycan composed of the basic structure of disaccharides (D-glucuronic acid and N-acetylglucosamine). Hyaluronic acid is widely present in the connective tissue, epithelial tissue and nerve tissue of the human body. It is an acidic mucopolysaccharide, which is one of the main components of the extracellular matrix.
With its unique molecular structure and physicochemical properties, hyaluronic acid shows a variety of important physiological functions in the body, such as lubricating joints, regulating the permeability of blood vessel walls, regulating proteins, water and electrolyte diffusion and operation, and promoting wound healing. Most importantly, hyaluronic acid has a special water-retaining effect, and it is the best moisturizing substance found in nature, and is called an ideal natural moisturizing factor.
Studies have found that the maturation and aging process of human skin also changes with the content and metabolism of hyaluronic acid. It can improve skin nutrition metabolism, make skin soft, smooth, wrinkle-free, increase elasticity, and prevent aging. It is moisturizing at the same time. Good transdermal absorption enhancer. Used in conjunction with other nutrients, it can play a more ideal effect in promoting nutrient absorption. It can be seen that hyaluronic acid is one of the basic components in human tissues, so it is safe to inject hyaluronic acid.
According to my years of injection experience, the side effects that my friends are concerned about are nothing more than the following aspects:
1. Will it affect or impair erectile function?
The layer of hyaluronic acid injection is outside the subcutaneous fascia layer of the penis, that is, outside the corpus cavernosum. As long as the injection doctor is familiar with the local anatomical layer and skilled in the technique, it is almost impossible to damage the corpus cavernosum, so it will not cause normal erectile function. influence. However, if the injection doctor lacks relevant knowledge and practical experience, and mistakenly injects hyaluronic acid into the cavernous body, it will cause hematoma in mild cases, and it will indeed damage erectile function in severe cases. Therefore, it is particularly critical to choose a regular hospital professional doctor for injection.
2. Will it affect the hardness after erection? As mentioned in my previous article, the principle of hyaluronic acid injection thickening can be understood as thickening the subcutaneous tissue layer of the penis, putting a thick "coat" on the penis. Hyaluronic acid injection does not affect the cavernous tissue, therefore, the hardness of the penis after erection is closely related to the texture of hyaluronic acid.
At present, medical hyaluronic acid can be divided into three categories: low molecular weight, medium molecular weight and high molecular weight. However, this is a common name, which is not strictly accurate. However, since this name has been deeply rooted in the hearts of the people, we will follow . We know that as the "molecular weight" increases, the texture of hyaluronic acid is harder and more suitable for filling operations. According to my personal experience, both medium molecular weight and high molecular weight hyaluronic acid can be used for thickening treatment. Under the premise of equal injection, high molecular weight hyaluronic acid has less impact on hardness and can be ignored. The only disadvantage is that the price is slightly lower. higher than medium molecular weight hyaluronic acid.
3. Will there be a foreign body sensation after the injection?
Friends who have been injected with hyaluronic acid have more say in this question. According to their feedback, after a 1-week edema period, no foreign body sensation was found at the injection site. Theoretically, hyaluronic acid, as one of the constituents of human tissue, does not have antigenicity, sensitization and pathogenicity. Under the premise of reasonable injection, there will be no foreign body sensation.
4. Will the appearance be unnatural after injection?
As far as I am concerned, the so-called unnatural appearance is the loss of harmony and beauty, and the most common situation is that it is too much. Although hyaluronic acid is an excellent material for penis injection and thickening, excessive injection will definitely cause the local tissue to be too bloated, and the proportion of the head of the penis will be out of balance, resulting in an obvious sense of incongruity. Therefore, in addition to excellent injection techniques, doctors also need to have aesthetic cultivation, accurately grasp the injection dose, and strike a balance between natural appearance and thickening effect.
In 2019, Korean scholars published an article on The Journal of Sexual Medicine, AComparisonoftheEfficacyandSafetyBetweenHyaluronicAcidandPolylacticAcidFillerInjection inPenileAugmentation:AMulticenter,Patient/Evaluator-Blinded,RandomizedTrialThis paper explores the efficacy and safety comparison of hyaluronic acid and polylactic acid injection in penile enlargement, which is a Multicenter randomized controlled study.
This study compared the subjects' satisfaction with the appearance of the penis before and after hyaluronic acid injection. After the injection, the subjects' satisfaction score increased rapidly and remained at a high level until the end of the follow-up period. The score of the hyaluronic acid injection group changed more significantly.
5. Will hyaluronic acid flow and deform in the body?
In terms of physical properties, hyaluronic acid does have fluidity, and the concerns of flow and deformation in the body after injection are by no means unfounded. But at the same time we need to know that hyaluronic acid is very different in vitro and in vivo. After hyaluronic acid is injected into the human body, after 2 to 4 weeks of shaping, a fibrous package will be formed in the body, which is what we usually call a capsule to avoid the occurrence of fluidity. In addition, good injection techniques can also avoid the displacement of hyaluronic acid in the body.
In order to avoid the displacement of hyaluronic acid in the body and improve the satisfaction of treatment, my experience is that the following points can effectively prevent the flow and deformation of hyaluronic acid after injection.
(1) The choice of hyaluronic acid. Try to use hyaluronic acid with a high degree of cross-linking. This type of hyaluronic acid has low fluidity and strong plasticity, which can effectively reduce fluidity from the perspective of materials.
(2) The choice of injection technique. The original local anesthetic tissue swelling combined with hyaluronic acid mesh injection technology can make the hyaluronic acid evenly distributed in the filling area, and significantly reduce the disadvantages of agglomeration and agglomeration of the filling material.
(3) properly bandaged. The fusion of hyaluronic acid and surrounding tissues takes a certain amount of time, usually 7-10 days according to personal experience. During this period, erections and daily squeezing can cause the filler material to flow and deform. Therefore, after the injection is completed, an elastic bandage needs to be used to properly fix the penis, and a mild compression bandage is required. As long as the above three points are grasped, the problems of flow and deformation can be solved immediately.
6. Will it affect the feeling of sexual life after injection?
In sexual life, male feelings are mainly conducted by the dorsal nerve of the penis. The exact location of the dorsal nerve is shown in the figure below.
In the process of hyaluronic acid injection, most of the fillers are distributed in the space between the superficial fascia of the penis and the tunica albuginea, that is, below the dorsal nerve; a small part is distributed between the skin and the superficial fascia, that is, located in the back above the nerve. Although this part of hyaluronic acid increases the distance between the dorsal nerve and the skin to a certain extent, it is suspected of weakening the nerve conduction, but for men with normal sexual function, its impact is negligible.
As mentioned above, Korean scholars published an article on The Journal of Sexual Medicine, and also conducted a research and analysis on the sexual life satisfaction of the research subjects before and after the injection. The results showed that the satisfaction score of the patients after the injection not only did not decrease, but increased to a certain extent. rise.
The reason is that the hyaluronic acid located between the skin and the superficial fascia has a certain "insulation" effect and reduces the sensitivity of the dorsal nerve, so it has a certain therapeutic effect on some patients with premature ejaculation, but whether there are other The mechanism remains to be further studied and explored.
